Physiotherapists work in many different areas of healthcare. Orthopaedic physiotherapy practice deals with musculoskeletal issues of the body such as pain, movement problems, weakness, and recovery from injury. Areas commonly treated include the spine, knees, shoulders and hips. Physiotherapists are experts in the assessment and treatment of movement problems and pain.

Injuries are common when participating in sports. They can range from traumatic injuries from sudden impact, to overuse injuries from repetitive strain. Physiotherapists commonly work with athletes and sports participants of all ages and ability to assist in faster recovery and return to sports, and for the prevention of re-injury. Other considerations for sports-injury recovery include a graded return to training.

Manual therapy, also known as mobilization or manipulative therapy, is a form of hands-on treatment where a physiotherapist carefully moves the tissues and joints of the body to restore movement and relieve pain. Research indicates that manual therapy can be beneficial for recovery from many musculoskeletal issues and injuries, including damage to the nervous system such as a pinched nerve.